Why Half-Life Matters with Antidepressants: 1. Short Half-Life = Faster Exit, Higher Withdrawal Risk 2. Long Half-Life = Slower Exit, Smoother Withdrawal Half-Life Impacts: Example Breakdown: Antidepressant Half-Life (approx.) Withdrawal Risk Prozac (fluoxetine) 4–6 days Low Zoloft (sertraline) ~1 day Moderate Effexor (venlafaxine) 5 hours High Paxil (paroxetine) ~21 hours…